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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLIC1
All Species:
29.39
Human Site:
T222
Identified Species:
64.67
UniProt:
O00299
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00299
NP_001279.2
241
26923
T222
A
R
E
E
F
A
S
T
C
P
D
D
E
E
I
Chimpanzee
Pan troglodytes
XP_531547
656
67911
T637
A
R
D
E
F
T
N
T
C
P
A
D
Q
E
I
Rhesus Macaque
Macaca mulatta
XP_001089326
288
31855
A267
V
H
R
H
L
S
N
A
Y
A
W
E
E
S
A
Dog
Lupus familis
XP_532079
241
27001
T222
A
R
E
E
F
A
S
T
C
P
D
D
E
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1Q5
241
26994
T222
A
R
E
E
F
A
S
T
C
P
D
D
E
E
I
Rat
Rattus norvegicus
Q6MG61
241
26962
T222
A
R
E
E
F
A
S
T
C
P
D
D
E
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425551
670
70209
T651
A
R
D
E
F
T
N
T
C
P
A
D
Q
E
I
Frog
Xenopus laevis
NP_001082687
240
26776
T221
K
R
E
E
F
A
S
T
C
P
D
A
A
E
I
Zebra Danio
Brachydanio rerio
NP_997847
241
26947
T222
A
R
E
E
F
S
S
T
C
P
S
D
E
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45405
238
27507
R218
T
E
L
K
D
T
P
R
L
S
A
K
D
R
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P04907
222
23831
A201
A
W
W
E
A
I
A
A
R
P
A
F
Q
K
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25
68
98.3
N.A.
98.3
98.7
N.A.
N.A.
24.7
74.2
75.9
N.A.
N.A.
N.A.
20.7
N.A.
Protein Similarity:
100
28.6
72.9
99.1
N.A.
100
100
N.A.
N.A.
28.2
83.4
85.4
N.A.
N.A.
N.A.
36
N.A.
P-Site Identity:
100
66.6
6.6
100
N.A.
100
100
N.A.
N.A.
66.6
80
86.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
86.6
26.6
100
N.A.
100
100
N.A.
N.A.
86.6
80
93.3
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
20.3
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
41
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
40
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
73
0
0
0
10
46
10
19
0
10
37
10
10
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
73
0
0
0
0
0
0
% C
% Asp:
0
0
19
0
10
0
0
0
0
0
46
64
10
0
0
% D
% Glu:
0
10
55
82
0
0
0
0
0
0
0
10
55
73
0
% E
% Phe:
0
0
0
0
73
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
73
% I
% Lys:
10
0
0
10
0
0
0
0
0
0
0
10
0
10
0
% K
% Leu:
0
0
10
0
10
0
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
28
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
82
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
28
0
0
% Q
% Arg:
0
73
10
0
0
0
0
10
10
0
0
0
0
10
0
% R
% Ser:
0
0
0
0
0
19
55
0
0
10
10
0
0
10
0
% S
% Thr:
10
0
0
0
0
28
0
73
0
0
0
0
0
0
10
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
10
10
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _